Title (English)
Carbon nanotube‑ and hydroxyapatite‑coated implants: histomorphometric assessment in a rabbit model
Thong tin bai bao / Article info
- Tac gia / Authors: Amira S. Eissa, Haitham Mohammed Abou Eleneen, Aya S. Sedik
- Tap chi / Journal: BMC Oral Health
- Ngay xuat ban / Published: 2026-06-16
- DOI: 10.1186/s12903-026-08811-8
- Nguon / Source: OpenAlex
Abstract (English)
Abstract Objective This study aimed to investigate whether the integration of functionalized carbon nanotubes (CNTs) with hydroxyapatite (HA) could create a bioactive nanocomposite capable of enhancing the early stages of osseointegration. Specifically, we investigated whether the high surface area and nanoscale structure of CNTs, combined with the osteoconductivity of 1% HA, could significantly enhance bone-to-implant contact (BIC) and new bone area (NBA) compared to traditional titanium surfaces in a mandibular model. Methods Here we evaluated the osseointegration of titanium implant discs coated with CNTs and CNTs combined with 1% HA in a rabbit mandibular model. Thirty rabbits received uncoated, CNT-coated, or CNT- HA coated titanium discs implanted into mandibular defects. After 4 weeks, bone-to-implant contact (BIC) and new bone area (NBA) were assessed histomorphometrically. Results Both CNT and CNT- HA coatings significantly increased BIC and NBA compared to uncoated implants ( p < 0.05), with no significant difference between coated groups. Conclusion CNT-based coatings enhance early osseointegration of titanium implants, while the addition of 1% HA does not confer additional benefit within 4 weeks, suggesting CNT coatings alone may improve implant integration effectively.
Doc bai day du / Read full article
Bai dang tu dong boi plugin Ortho OA Fetcher. Anh (neu co) tu PubMed Central. Noi dung lay tu nguon open access va dich tu dong – chi mang tinh tham khao.
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